The Eastern Region of South Dakota has some of the most populated cities in the state, abundant with culture and attractions.  Cities in South Dakota's eastern region range from very small towns to the state's largest city, Sioux Falls, and everywhere in between.

Top Eastern Region Cities:

• Sioux Falls
• Aberdeen
• Watertown
• Brookings
• Mitchell
• Huron
• Vermillion
• Yankton

Aberdeen

A bustling urban community, Aberdeen is home to a wide variety of thriving businesses, shopping districts, schools, and industries. The sprawling Lakewood Mall is a hub for visiting and resident shoppers, who can also explore the charm of historic downtown Aberdeen. Learn more about Aberdeen.

Arlington

Canton

Canton, South Dakota, population 3,220, is located just 10 miles east of Interstate 29 on US Highway 18 and is approximately 20 miles south of Sioux Falls. A strong Norwegian heritage dominates its historical roots. Restored historical buildings in the business district add to the flavor of its history. Learn more about Canton.

Centerville

Centerville is a family-oriented town with agricultural roots and is known by its' Scandinavian heritage. Located in the center of several metropolitan areas, Centerville is ten miles west of Interstate 29 in southeastern South Dakota. Learn more about Centerville.

Clark

The potato is king in Clark, South Dakota where local farmers grow bushels of the tasty tuber. That's why each year the town throws a party in honor of its favorite over-used, under-appreciated starch. The first Potato Festival in Clark was held in 1972.  Learn more about Clark.

Clear Lake

Clear Lake is a rural South Dakota community with strong traditional values. Located in the heart of Deuel County, Clear Lake's population is nearly 1,335 friendly residents and continues to grow each year. Annually the Crystal Springs Rodeo Parade is held in Clear Lake. Learn more about Clear Lake.

Colman

The busy city of Colman is located just 2.5 miles west of Interstate 29 at Exit 109 and centrally located between the cities of Madison, Brookings, Sioux Falls and Pipestone, Minnesota. An acquisition of 144 acres on the southeast corner of town will be residential property and commercial lots are available on SD Highway 34. The city's current population is about 600 people. Learn more about Colman.

Dell Rapids

Welcome to Dell Rapids, South Dakota, home of the Dells of the Big Sioux River. On behalf of its' residents, we extend this invitation for you to get to know our fine community. Learn more about Dell Rapids.

Elk Point

Over the years, Elk Point has produced many prominent businessmen, political leaders and community-spirited citizens. As Elk Point dawns 150 years, the city’s governmental, business and civic leaders are dedicated to maintaining current momentum and continuing to improve the quality of life in the community. Learn more about Elk Point.

Freeman

Located in southeastern South Dakota, in the center of a triangle formed by Sioux Falls, Yankton and Mitchell, Freeman has a population of about 1,300 and serves the larger community. Learn more about Freeman.

Garretson

Welcome to Garretson, SD. You'll find nature at its finest only 20 minutes northeast of Sioux Falls just north of I-90. Explore red quartzite pinnacles and chasms along Split Rock River in three Garretson parks. Back road scenery, geology, history of prairie pioneers and legendary bandits Jesse and Frank James are waiting for you to discover in Garretson. Learn more about Garretson.

Groton

Groton is more than 100 years old and has weathered changes of the times and the challenges of nature.  Learn more about Groton.

Harrisburg

Harrisburg is a place of ever growing possibilities from growing developments, industrial park and a quality school system. Learn more about Harrisburg.

Hartford

As a town of 2,300 people, Hartford offers the feel of the small community with the excellent benefits of the city of Sioux Falls within a 10 mile commute. Learn more about Hartford.

Henry

Henry is a small and friendly community located in northeastern South Dakota. It is 17 miles west of Watertown on Hwy 212. Learn more about Henry.

Humboldt

Approximately twenty miles west of Sioux Falls, Humboldt serves its' 500 residents with hospitality of the Midwest. Learn more about Humboldt.

Huron

Huron is a wonderful place to live, work, play and raise a family. With a population of approximately 12,000, we are known for our outstanding school system (both public and private), a state-of-the-art Medical Center, the Huron Event Center and the Arena. Learn more about Huron.

Letcher

Thirty miles northwest of Mitchell nestles the vibrant community of Letcher. Letcher has an official population of 177 from the 2000 Census and a growing population of approximately 200. Learn more about Letcher.

Madison

A hub for arts, culture, and outdoor recreation, the historic town of Madison is committed to maintaining an excellent quality of life for its residents. Learn more about Madison.

Menno

Menno owes its beginnings to the railroad industry. A railroad line was necessary to transport livestock and grain to market. In 1879 the Chicago, Milwaukee and St. Paul Railroad began laying tracks through the area. The commerce the railroad brought to the area resulted in the towns of Menno and Freeman being laid out. Learn more about Menno. Learn more about Menno.

Milbank

Milbank has an active community that is growing and changing while still keeping their traditions alive. Milbank is a town located in northeast South Dakota with a population of 3,640 and is located in Grant County which has a population of 7,847. Milbank is located 10 miles from Big Stone Lake and is surrounded by farmland. Learn more about Milbank.

Mitchell

Home to the famous Corn Palace, Mitchell is home to nearly 15,000 residents, but draws approximately half a million visitors each year. The city’s economy is supported almost exclusively by its tourist income. Learn more about Mitchell.

Parker

Parker is home to more than one thousand people who enjoy the safety and convenience of living in a smaller area. Located 25 minutes from Sioux Falls, Parker offers an atmosphere of community. Learn more about Parker.

Parkston

Parkston provides retail, medical, professional, educational and recreational opportunities. Parkston has fertile farmland to help with the agricultural community as well the hunting season for pheasants, deer and other wildlife, as well as a vibrant manufacturing sector.  Learn more about Parkston.

Salem

Salem, South Dakota is a progressive community that welcomes new residents and businesses. There is a wide variety of local businesses for shopping, and every penny spent locally not only helps the city fix streets, plow snow or run the parks and summer recreation programs; it also keeps local business thriving in town. Learn more about Salem.

Sioux Falls

The largest city in South Dakota, Sioux Falls is known state-wide as a thriving urban hub. Home to 200,000+ residents, the city boasts an abundance of shopping, dining, and entertainment opportunities, as well as scenic parks for outdoor enthusiasts. Learn more about Sioux Falls.

Tea

Tea is known as the home of Pole Vault Olympian Derek Miles. It's a booming community that is located fifteen miles southeast from Sioux Falls and rests between Interstate 29 and Highway 17.  Learn more about Tea.

Vermillion

Nestled in the southeastern corner of South Dakota, the area now known as Vermillion was first explored by fur traders in the 1700s and was utilized as a campsite by Lewis and Clark during their expeditions in the summer of 1804. Officially incorporated as a city in 1873, Vermillion is the tenth largest city in the state and is the county seat of Clay County.  Learn more about Vermillion.

Volga

Drive through Volga and discover friendly neighborhoods, tree-lined streets, and impressively landscaped yards. Learn more about Volga.

Watertown

The state’s fourth largest city and the county seat of Codington County, Watertown is nestled in Northeastern South Dakota along the Big Sioux River. Considered a highly livable, family-friendly location, the city is heralded for its safe, quiet environment and low crime rate.  Learn more about Watertown.

Yankton

Nestled along the Missouri River and often referred to as “River City,” Yankton earned a place in history by serving as a layover for steamboats during the Black Hills Gold Rush. Learn more about Yankton.

Want to see more?  Click here to see all South Dakota cities.